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Cactus (Opuntia Streptacantha) Soluble DietaryFiber Suppress Elevation of Postprandial Blood Glucose Levels inType II Diabetes Rats

Tadasu FURUSHO1, HiroshiISHIDA1, Hiroko SUZUNO1*
MorifumiSAITO2, Yumi MINARI3, NoritakaTOKUI4,
and Satoshi INNAMI5

1Department of Nutrition, Jr. College of TokyoUniversity of Agriculture
2lchiban-Foods Co .Ltd.
3Department of Nutritional Science, Faculty ofNutritional Science, Nakamura Gakuen University
4lnstitute of Industrial Ecological Sciences, Universityof Occupational and Environmental Health
5Department of Applied Biology and Chemistry , Facultyof Bio-Science, Tokyo University of Agriculture

 The present paper was attempted to examine the effect of awater-soluble dietary fiber (SDF) extracted from OpuntiaStreptacantha (OpS) on postprandial blood glucose level. A OpS-SDFwas extracted from the hot-dried OpS powder. An elevation of thepostprandial blood glucose level in GK rats (a Type II diabetesmodel animal) given 0.2, 1 or 2% OpS-SDF solution orally togetherwith 20% glucose solution was significantly suppressed as comparedwith that observed in the control rats given only glucose solution.The diffusion rate of glucose and the permeation rate of glucose inthe cultured CAC0-2 cells were significantly reduced by theaddition of OpS-SDF as compared to the control. Further, in theexamination on the physico-chemical characteristics of OpS-SDF, weobtained that the glucose diffusion inhibition rates of the 0.2 or0.5% OpS-SDF solution was markedly high compared with that of purewater. The viscosity of 2% OpS-SDF solution was found to be about3,000 times high compared with that of pure water. It was revealedthat OpS-SDF in OpS is a kind of mucilaginous SDF and has thesignificant suppressing effect for elevation of postprandial bloodglucose level.

Key words: cactus, soluble dietary fiber, postprandial bloodglucose, rat(s), CAC0-2 cell,


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