Effect of Dietary Fibers on Accumulation of Hexachlorobenzene in Rats Yuko SAITOH1，Sachie IKEGAMI1＊ 1Department of Food Science, Faculty of Home Economics, Otsuma Women’s University | Three experiments were conducted to examine the effects of dietary fibers on accumulation of environmental pollutants. In Exp. I, male Sprague Dawley male rats, aged 5 weeks, were fed diets for 3 weeks containing 100 μg/100 g of hexachrolobenzene (HCB) and either cellulose (control group) or lecithin, soybean protein, diacylglycerol or tamarind gum. Accumulation of HCB in perirenal and epididymal fat was lower in rats fed tamarind gum compared with cellulose or the three other ingredients. Based on the results of Exp. I, a comparison of HCB accumulation with different dietary fibers (cellulose, guar gum, tamarind gum, sodium alginate, and chitosan) was carried out in Exp II. A significant reduction in HCB accumulation in adipose tissues was observed in rats fed the four dietary fibers compared with those fed cellulose. These two experiments suggested that feeding dietary fibers may reduce the accumulation of HCB in adipose tissues. Exp. III was conducted to determine the effect of dietary fibers on elimination of HCB from adipose tissues. In this experiment, after being fed the HCB diet for 3 weeks, the rats were fed diets containing either cellulose, tamarind gum or chitosan without HCB for 10 or 20 days. After feeding, there was only a small decrease in accumulation of HCB, with no significant difference between the three dietary fibers. These results suggest that feeding of dietary fibers may reduce accumulation of HCB in adipose tissues. It is possible that the mechanism of this effect is associated with transfer of fat to adipose tissues. Key words : dietary fiber, hexachlorobenzene, adipose tissue, accumulation, tamarind gum. |
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