Effect of Corn Soluble Dietary Fiber on BloodPressure in Human
and Spontaneously Hypertensive Rats Sachie IKEGAMI1, SaekoOHSAWA1, Keiko ISII2, SetsukoHONDA3,
Sumiko NAGAYAMA4 and Michio YAMAGUCHI5 1Divsion of Food Science, National Institute of Healthand Nutrition
2Division of Health Promotion, National Institute ofHealth and Nutrition
3Minamihama Clinic
4Faculty of Homeeconomics, Tokyo KaseigakuinUniversity
5Faculty of Human Life Sciences, Jissen Women'sUniversity This study was performed to clarify the effect ofcorn soluble dietary fiber(CSD) on blood pressure of human andexperimental animals. CSD contained 83.6% soluble dietaryfiber.
Eighteen subjects received 5 g CSD as a solution of hot water inevery meal during 4 weeks. They were divided into two groups bytheir systolic blood pressure. The groups were mild hypertensiongroup of 6 subjects over 140mmHg and normal group of 12 subjectsunder 140mmHg, respectively. Systolic and diastolic blood pressuresin hypertension group showed significant reduction by the treatmentof CSD. However, no significant effect was observed in the normalgroup.
On the other hand, spontaneously hypertensive rats(SHR) were usedin the animal experiment. SHR rats were divided into two groups.SHR rats received ad libitum 5% solution in CSD group and distilledwater in the control group during 10 weeks. Blood pressure in CSDgroup was significantly supressed from 1 week after starting thetreatment.
The specific role of the dietary fiber in the regulation of bloodpressure certainly merits more carefully and criticalevaluation.
Key Words : corn soluble dietary fiber, systolic blood pressure,diastolic blood pressure, hypertension, spontaneously hypertensiverats |
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