ユーザーID :
パスワード :
総 説

運動と自然免疫と腸内細菌

矢野博己1,2*,渡邉知央2,青木孝文3,長野隆男4,小栁えり1

1川崎医療福祉大学医療技術学部健康体育学科
2川崎医療福祉大学大学院医療技術学研究科健康科学専攻
3川崎医療福祉大学医療技術学部臨床栄養学科
4石川県立大学生物資源環境学部食品科学科

The “Open window theory” proposes that high-intensity exercise causes immediate temporary immunosuppression, which increases the risk of upper respiratory tract and other infections. In this review, we discuss the following items:(a) Immunosuppression after intense exercise is physiologically significant. (b) Intense exercise-induced immune activation in the gastrointestinal tract may also be physiologically significant. We refer to these apparently conflicting phenomena as the “Super homeostasis theory.” Furthermore, in our view, the ability of the gut microbiota to produce short-chain fatty acids from dietary fiber as a survival strategy may be associated with the “Super homeostasis theory.”
Key Words: Open window theory, Toll-like receptors, Super homeostasis theory, gut microbiota, dietary fiber.

戻る