Effect of Oatmeal Porridge Supplementation onSerum Cholesterol Levels in Japanese Men With Boundary and MildHypercholesterolemia: Evaluation of Efficacy and Safety Yasuhiro TOBA1, FumiHATAMOTO2, Satoko KINOSHITA3, ToshiakiUCHIDA3, Taishi ODA1,
Keiko ISHII2, Seiichiro AOE2, YutakaSUZUKI1, Takashi FUJITA1, and ShuichiTSUJI4 1Technology and Research Institute
2Product Planning Department
3Dairy Foods Planning and Development Department, SnowBrand Milk Products Co., Ltd.
4Eminecross Medical Center A randomized double blind study was conducted on36 adult Japanese men (averaged age: 40 years old) with boundaryand mild hypercholesterolemia to clarify the effect of oatmeal onthe serum cholesterol and the safety of its long-term intake. Thesubjects were randomly divided into 2 groups. The oatmeal group wasgiven the oatmeal porridge containing 45g oatmeal (1.6gβ-glucan) each once a day for 12 weeks, and the controlgroup was given the control porridge containing white rice andcellulose as the substitute for oatmeal. As a result, the level ofserum total cholesterol (TC) in the control group tended toincrease as compared to the front period of ingestion (p=0.053).The level of serum TC in the oatmeal group did not change, and wassignificantly lower than that in the control group throughout theingestion period (p<0.05). From the results of physiologlcal andbiochemical examinations, and the check of subjective symptoms,there was no negative effect in the group given oatmeal porridgeexcept for loose feces. These results indicate that oatmealcontaining P-glucan can modulate the level of serum TC and issafety food.
Key words: Catmeal, P-glucan, serum cholesterol,hypercholesterolemia |
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