This pilot study was conducted to examine the effects of a newly-developed jelly containing polydextrose on hyperglycemia and defecation frequency in diabetic patients undergoing maintenance hemodialysis (DM-HD patients). DM-HD patients on insulin were orally given the jelly containing 7 g of polydextrose twice a day at meal times for 4 or 12 weeks. Postprandial blood glucose levels were significantly decreased after a 4 week-treatment with the jelly, compared with levels before treatment started. Random blood glucose and HbA1c levels were significantly decreased after 12 weeks treatment with the jelly. In addition, increased defecation frequency was observed during the ingestion period of the jelly. The patients’ preferences questionnaire did not show any noticeable problems with long-term ingestion of the jelly. Taken together, these findings suggest a new treatment option for the control of blood glucose and defecation in DM-HD patients.
Key words ; Diabetes Mellitus, Dietary fiber, Hemodialysis, Hyperglycemia, Polydextrose |
