イヌリン・ホエイ混合物が便秘傾向を有する健常成人男女の排便状態および腸内細菌叢に及ぼす影響 葛西大介1, 2，梅沢 晃2，輿水美奈2，佐々木香子2，大庭 潔2，菊地裕人3，
内野浩克3，赤部紀夫4，韓 圭鎬1, 5，島田謙一郎1, 5，福島道広1, 5 ＊ 1岩手大学大学院連合農学研究科
2公益財団法人とかち財団
3日本甜菜製糖株式会社総合研究所
4株式会社十勝野フロマージュ
5帯広畜産大学食品科学研究部門 A mixture of inulin and cheese whey liquid (MIW), was developed to effectively use the waste liquid of cheese whey from small-scale cheese making. In this study, we examined the effect of MIW on the intestinal environment and bowel movement. The effects of MIW on physical measurements, blood pressure, blood examinations, defecation, fecal properties, and intestinal microbiota were investigated in 20 healthy adult men and women (10 men and 10 women; mean BMI 22.3 ± 3.34 kg/m2) with mild constipation. The subjects were divided into two groups (placebo and MIW ingestion groups). Each subject in the MIW group was administered 30 g/day of MIW for 28 days after a non-intake period of 14 days. There were no clinical problems during the intake period in both groups. Although the fecal properties and intestinal microbiota were not significantly different in both groups during the intake period, the frequency of defecation increased significantly (p<0.05) in the MIW intake group compared with the placebo group. These results suggest that MIW improved the state of bowel movements in healthy adults with mild constipation.
Key words: whey, inulin, fecal microbiota, defecation, constipation |
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