Polydextrose has been reported to promote bowelelimination. The clinical efficacy of polydextrose administered ata daily dose of 7g for 30 days was examined in 23 patients withhabitual constipation and melanosis coli found by totalcolonoscopy. After the start of treatment with polydextrose,13(56.5%) of the 23 patients noted improvement in constipation(dyschezia). The stool consisitency of stools improved in 17(85.0%) of 20 patients having had hard stools. The frequency ofdefecation increased in 13 (81.3%) of 16 patients who of fecalproperties. After the use of polydextrose for 30 days, the effectsof polydextrose was noted in 20(87.0%) of the 23 patients in totalas (1) improvement in constipation, (2) increased frequency ofdefecation, (3) softened the stool consisitency, (4) improvement inother bowel symptoms, or (5) reduced laxative dose, or two or moreof those. These results indicated a clinical effects ofpolydextrose for the treatment of habitual constipation in patientswith melanosis coli.
Key words: polydextrose, habitual constipation, melanosis coli |
